Analysis of [3′,3′-d2]-nicotine and [3′,3′-d2]-cotinine by capillary liquid chromatography–electrospray tandem mass spectrometry
نویسندگان
چکیده
منابع مشابه
Analysis of nicotine, 3-hydroxycotinine, cotinine, and caffeine in urine of passive smokers by HPLC-tandem mass spectrometry.
BACKGROUND A method is described for the simultaneous analysis of nicotine and two of its major metabolites, cotinine and 3-hydroxycotinine, as well as for caffeine from urine samples. The method was developed to assess exposure of restaurant and hotel workers to environmental tobacco smoke. METHODS The method includes sample pretreatment and reversed-phase HPLC separation with tandem mass sp...
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ژورنال
عنوان ژورنال: Journal of Chromatography B
سال: 2007
ISSN: 1570-0232
DOI: 10.1016/j.jchromb.2007.06.018